Just when it feels like social media has started to cool down on the most reckless viral trends, an old and dangerous one is finding new life.

Doctors and public health officials are once again sounding the alarm over the “Benadryl Challenge,” a viral social media trend that first gained attention around 2020 and is now showing signs of resurfacing across platforms like TikTok.

The premise is as dangerous as ever.

Getty Images
Getty Images
Getty Images

The Benadryl Challenge

Participants intentionally take excessive amounts of diphenhydramine (the active ingredient in Benadryl) in an attempt to trigger hallucinations or a drug-like high. Medical experts warn that the line between experimentation and overdose is frighteningly thin, especially for teens.

Emergency room visits, severe poisoning cases, and at least one confirmed teen death have been linked to the trend, prompting repeated warnings from the FDA and pediatric specialists. Overdoses can cause rapid heart rate, seizures, confusion, coma, and in the worst cases, fatal heart rhythm disturbances.

What makes the current resurgence especially troubling is that it is happening in an environment where families assumed the worst of these “challenge” fads had already peaked. Yet researchers note the trend never fully disappeared, it simply went quiet for a time before reappearing in new posts and reposted content.

This challenge definitely gets red-flagged. (Getty Images)
This challenge definitely gets red-flagged. (Getty Images)
This challenge definitely gets red-flagged. (Getty Images)

This Challenge Joins The List Of Past Challenges And Stunts That Have Gone Wrong

Things like the Tide Pod Challenge (detergent ingestion), the Blackout Challenge (oxygen restriction), the Milk Crate Challenge (fall injuries), the Fire Challenge (self-ignition), and the Skull Breaker Challenge (trip-and-fall trick assaults). Each began as social media spectacle and ended with hospital visits or worse.

For Illinois families, the issue feels especially immediate in a state where schools and parents are already grappling with how much influence smartphones have on student behavior. The fear among health officials is that a single reposted video can reach a new wave of kids who weren’t even in middle school during the trend’s original outbreak.

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