CHICAGO (AP) — Democratic U.S. Rep. Tammy Duckworth of Illinois says she'll run for U.S. Senate in 2016, setting up a high-profile challenge to Republican Sen. Mark Kirk's re-election bid.

In a video posted Monday on her campaign website, Duckworth says it's time for "Washington to be held accountable."

Duckworth is serving a second term in Illinois' 8th District, which covers suburbs west and northwest of Chicago. The Iraq War veteran and double amputee was elected to the House in 2012.

Kirk is in his first term and intends to focus his campaign in part on his recovery from a stroke.

Illinois is Democrat-friendly territory, and Duckworth's campaign could represent one of the best chances for Democrats nationwide to pick up a seat as they try to regain Senate control.

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